At first sight, the anime seemed like a fun hilarious anime with kyoushi junior, however when the 'demon eyed kyo' takes over the anime starts in a much more serious tone, which prevails till the end.
The story has its twists, but when you think that the 'last boss' is defeated, more villians pop up. Samurai Deeper Kyo has an unique and bizarre take on edo history, and the battles between samurai. Thus begins a grand tale of legendary two swordsmen and the discovery of their secrets. This encounter awakens 'Demon Eyes' Kyou, whose mind has been trapped inside of Kyoushirou's body ever since that fateful battle. On her way to claim his bounty, they are attacked by an inhuman monster that seeks to devour Kyoushirou. Samurai Deeper Kyou begins four years after that battle, when a gun-wielding bounty hunter by the name of Yuya Shiina hunts down Kyoushirou-now a perverted, traveling medicine-man who has built up a large debt. Their legendary clash was cut short when a meteor from the heavens fell down upon that battlefield, leaving both to vanish in its wake.
The other was the thousand-man slayer, with eyes and hair the color of blood, 'Demon Eyes' Kyou. One was Kyoushirou Mibu, a skilled and noble warrior in possession of the unique powers of the Mibu Clan. In the year 1600, at the fog-covered battlefield of Sekigahara, a fierce battle was waged by two exemplary swordsmen.